Applied Trophology, Vol. 1, No. 2
(February 1957)

Contents in this issue: “Acidosis and Alkalosis,” “New Aid for Incurable Disease Told,” “Chlorophyll Ointment Heals Decubitus Ulcers,” “Choline Prevents Fatty Change and Cirrhosis in the Livers of Dogs Subjected to Hypophysectomy and Thyroidectomy,” “Lipid Content and Volume of Bile Secreted by Choline-Deficient Rats with Fatty Livers,” “Items of Interest (The Pancreas and Cholesterol),” “Potassium […]

Applied Protomorphology: The Physiological Control of Growth and Repair

By Dr. Royal Lee

Summary: In this eye-opening 1952 article, Dr. Royal Lee outlines the basic mechanism behind autoimmune disorders—something that alludes medical science to this day. Under normal circumstances, Dr. Lee writes, growth factors specific to each tissue in the body, which he calls “protomorphogens,” are released into the bloodstream by the tissues’ cells. To keep protomorphogens from causing runaway growth of their corresponding tissue, the body produces antibodies to neutralize them. When a tissue (or organ) becomes overworked, it begins to produce an abnormally high amount of its protomorphogen. This, in turn, causes the body to produce an abnormally high amount of antibodies. If the amount of antibody exceeds the amount of protomorphogen, the excess antibodies begin attacking the actual cells of the tissue—what has come to be known as an “autoimmune reaction.” Not only did Dr. Lee identify and explain such reactions over seventy years ago, he also developed food-based supplements that thwart them, as he describes in this article. With medicine still groping to explain why autoimmune reactions occur and at a loss as to how to stop them, Dr. Lee’s words are nothing short of astounding. 1952. 

The Chemical Background of the Relation Between Malnutrition and Heredity

By Dr. Royal Lee

SummaryIt’s been said that Dr. Royal Lee’s theories were typically fifty years ahead of their time. In this astounding lecture from 1956, the great pioneer of nutrition science presents two “radical” ideas now considered revolutions in scientific thought. First, Dr. Lee challenges the principle of classic genetics theory that, barring a mutation in a person’s DNA, that individual will pass on a clean genetic slate to his or her children. Instead, Dr. Lee states, any defect caused to a person during his or her lifetime by malnutrition is likely to be inherited by the individual’s future children—a fact thoroughly substantiated by the new science of epigenetics. Dr. Lee then discusses the science behind his remarkable Theory of Protomorphology, the first known account of autoimmune disorders. According to Dr. Lee’s theory, the growth and repair of body tissues is controlled by a careful balance between, on one hand, growth-promoting antigens produced by (and unique to) each type of tissue and, on the other hand, antibodies produced by the body’s autoimmune system. If the amount of antibodies exceeds the normal balance, then those antibodies attack the tissue—or an “autoimmune reaction” occurs. Though it would take decades for conventional science to catch up with Dr. Lee, today autoimmune reactions are considered a leading cause of disease and death in America. From Natural Food and Farming, 1956. 

How Antibody Attacks Cells

By Dr. Robert Dourmashkin

Summary: In the 1940s Dr. Royal Lee developed the Protomorphogen Theory through his pioneering recognition of the autoimmune disease process. This article, from a 1964 issue of New Scientist magazine, is among this first to photographically document the cellular destruction caused by a host’s own auto-antibodies. From New Scientist, 1964. Lee Foundation for Nutritional Research reprint 141.

Protomorphology: The Principles of Cell Auto-Regulation

By Royal Lee and William A. Hanson

Summary: The complete book on the subject of the Protomorphogen. In this seminal work, Dr. Royal Lee connects the dots between the endocrine, nutritional, and cellular control mechanisms of the living human cell as well as how growth and repair in the body are regulated. This is the basis for Dr. Lee’s theories of autoimmune disorders, in which he detailed the immune system’s ability and tendency, under conditions such as nutrient deficiency, to target the body’s own tissue. Lee’s visionary tome was released decades before any understanding of autoimmune disorder was acknowledged or accepted by medicine or any other field of healing. Lee Foundation for Nutritional Research, 1947.

View PDF: Protomorphology: The Principles of Cell Auto-Regulation

Chiropractic Reactions in the Light of Protomorphology

By Dr. George Goodheart

Summary: In this 1951 article, Dr. George Goodheart, founder of applied kinesiology (AK), discusses the Protomorphogen Theory of Dr. Royal Lee in relation to the mechanisms of chiropractic treatment. This is one of Dr. George Goodheart’s earliest professionally published articles. From The Journal of the National Chiropractic Association, 1951. Reprinted by the Lee Foundation for Nutritional Research