Vitamin F: 1926–1957

View PDF: Vitamin F Research 1926 to 1957 1926 Boissevain, C.H. “The Action of Unsaturated Fatty Acids on Tubercle Bacilli.” Boissevain reports experiments showing the effect of unsaturated fatty acids on the virulence of tubercle bacilli in vitro. (Compare with the work of Larsen on the ricinoleates.) Linoleic and linolenic acids were among the most […]

Applied Trophology, Vol. 1, No. 1
(January 1957)

The following is a transcription of the January 1957 issue of Dr. Royal Lee’s Applied Trophology newsletter, originally published by Standard Process Laboratories. Also in this issue: Science Discovers Vitamin E Oxidative Diets Cancer and Rancid Fats Items of Interest (Vitamin E in Infants) Tip of the Month (Cramps) Q&A High Points of Trace Minerals-B12, Antronex, Arginex, […]

The Vitamins in Medicine, Part 2 (Vitamins C, D, E, K and More)

By Franklin Bicknell, MD, and Frederick Prescott, MD

Summary: Nutrition and medicine have seldom seen eye to eye. Though the discovery of the vitamins in the early twentieth century did cause some physicians to grasp the profound connection between vitamin deficiencies and degenerative disease, medicine as an institution never truly embraced this idea. Ultimately, the American Medical Association declared—in concert with the industrial food industry and the U.S. Food and Drug Administration—that most Americans do not suffer vitamin deficiencies of any consequence. This position, however, contradicts decades of scientific study, as famed natural nutritionist Dr. Royal Lee argued throughout his career. One of the books Dr. Lee cited most often in making his case was the text here, The Vitamins in Medicine, by British physicians Drs. Franklin Bicknell and Frederick Prescott. Backed by over 4500 scientific references, the text sums the totality of scientific knowledge about the vitamins at the time of its publication in the mid-twentieth century. While the book does take some typically medical views of vitamins, e.g., that they are single chemical substances and not synergistic biochemical complexes, as Dr. Lee taught, it nevertheless supports strongly the notion that many, if not most, of our modern ailments stem from partial (or “subclinical”) vitamin deficiencies. “This book not only tells of the ravages caused by ignoring nature’s ways,” Dr. Lee said, “but it also shows us the way to prevent these bodily damages.” In this second part of the book, Bicknell and Franklin discuss vitamins C, D, E, and K (along with a few other vital, if lesser known, nutrients). In Part 1, the authors examine vitamin A as well as the various B vitamins. Though the information in this book is over seven decades old, it is still incredibly valuable today, when so few health practitioners actually know what the vitamins do—or what a lack of them can cause. Lee Foundation for Nutritional Research, 1953. Original publisher William Heinemann, London.

Vitamins F and F2

By Dr. Royal Lee

Summary: Few people today have heard of vitamin F, but back in the heyday of vitamin research, this fat-based complex and vitamin D synergist was widely recognized as an essential nutrient for the human body, obtainable only from food and ideally from animal fats. In this 1949 article, Dr. Royal Lee expounds the nature of vitamin F as a complex of compounds that includes—but is not limited to—the famous “essential fatty acids” of today’s nutrition, linolenic acid and linoleic acid. In vitamin F these two compounds work in tandem with a host of other cofactors, including the critical arachidonic acid, Dr. Lee explains, to promote such important actions as calcium transport, prostate function, immunity, and even cancer prevention. Moreover, he writes, when vitamin F combines with phospholipids (as occurs in mammalian livers), it forms a complex that exhibits different nutritional activity than that of vitamin F. This complex, which Dr. Lee calls vitamin F2, is intimately involved in the repair and generation of new tissue, making it vital for any therapy of “muscular dystrophies, creeping paralyses, anemic states, weakness, and atrophy.” While modern science continues to underplay vitamins and minerals, articles like this remind us that these essential micronutrients are involved in the most fundamental functions of the body, and even a slight deficiency in any one of them can have catastrophic consequences on our health.

Butter, Vitamin E, and the “X” Factor of Dr. Price

By Dr. Royal Lee

Summary: Could eating butter prevent hot flashes? Such a suggestion would sound outlandish to today’s nutrition “experts.” Yet not only did researchers in the mid-twentieth century show butter helps counter disorders associated with menopause, but the now maligned food was once regarded as a powerful healer in general, with physicians prescribing it for everything from psoriasis to tuberculosis. The reason for butter’s formerly stellar reputation is simple, explains Dr. Royal Lee in this wide-ranging 1942 publication. Butter is loaded with bioactive fat-soluble vitamins, including vitamins A, D, and E, and as Dr. Weston Price observed in his classic book Nutrition and Physical Degeneration, these nutrients are so critical to good health that human populations have historically placed a special emphasis on foods containing them. Butter produced by cows pasturing in the springtime is particularly nutritious, Dr. Lee adds, its deep yellow color indicating a high content of the famous “Activator X,” an elusive fat-soluble nutrient shown by Dr. Price to be essential for moving calcium from the blood into the bones and teeth. Given modern nutrition’s proscription against butter and other animal fats in the diet, it’s no wonder that today America is plagued by osteoporosis and other calcium-related disorders—not to mention the myriad other ailments Drs. Price and Lee would have predicted for a nation starving itself of fat-soluble vitamins. Published by the Lee Foundation for Nutritional Research, 1942.

Honey in Nutrition

By William Miller

Summary: An excellent overview of the value of raw honey. Author William Miller compares the nutritional qualities of this extraordinary food, manufactured by bees for millions of years, to those of refined sugar. His conclusion? They’re complete opposites nutritionally, with honey providing vitamins, minerals, and other factors critical for life and white sugar providing nothing more than empty calories. Lee Foundation for Nutritional Research reprint 119, 1955. Original source unknown.

The Special Nutritional Qualities of Natural Foods

By Dr. Royal Lee and Jerome S. Stolzoff

Summary: In this landmark report from 1942, Dr. Royal Lee and coauthor Jerome Stolzoff contrast the nutritional merits of traditional, natural foods and their industrially processed counterparts. Whereas the foods of traditional diets have centuries of trial and error behind them affirming their ability to nourish the human body, the authors say, industrially processed foods were introduced into the food supply practically overnight, with no nutritional testing whatsoever. Only when people in droves began developing vitamin-deficiency diseases—which include the likes of heart disease and cancer, Dr. Lee points out—did nutritionists of the early twentieth century begin to realize the frightening truth: processing and refining render food nutritionally unfit by irrevocably damaging its vitamin complexes, and unless the human race returns to a diet of time-tested natural foods, it will quite literally starve itself to death. Includes an eye-opening chart listing almost 150 modern diseases and the vitamin deficiencies associated with them by scientific research of the early twentieth century. Published by the Lee Foundation for Nutritional Research, 1942.

Fat and Its Utilization in Cholesterol Control

By Dr. George Goodheart

SummaryIn 1961 the American Heart Association (AHA) officially endorsed the “diet-heart hypothesis,” the idea that overconsumption of dietary fat increases the risk of heart attack. In particular the AHA condemned saturated fat, a type of fat found primarily in animal foods. Holistic health practitioners balked at the idea of this natural substance causing an unnatural condition such as heart disease and sensibly claimed that, if anything, synthetic fats such as hydrogenated fats and heat-processed plant oils—introduced just prior to the rise of the heart disease epidemic—were likely to blame. These natural healers proved to be prescient, as research in recent decades has shown a correlation between the consumption of hydrogenated fats and heart disease while failing to show such a connection for natural saturated fat. (Ironically, many of the early studies “supporting” the diet-heart hypothesis lumped hydrogenated fats and saturated fat into the same category.) In this article from 1965, famed chiropractor Dr. George Goodheart dispels myths about the diet-heart hypothesis—including the idea that cholesterol is a toxin—and explains why natural fats actually aid proper cholesterol metabolism, not hinder it. He goes on to suggest that overconsumption of refined carbohydrates, not natural fat, is likely the biggest dietary cause of heart disease—a hypothesis explored in scientific detail in the seminal 2007 book Good Calories Bad Calories. From the Digest of Chiropractic Economics, 1965. Lee Foundation for Nutritional Research form VH-1 75. 

Factors Favorable and Unfavorable to Cancer

By Dr. Royal Lee

Summary: In this brief but poignant passage, Dr. Royal Lee observes that cancer tends to develop only in people with a weakened or imbalanced endocrine system. Healthy thyroid function in particular, he says, is critical in defending against the disease. This includes optimizing the effect of the gland’s hormone thyroxine by ensuring adequate levels of vitamin F, a complex of fatty acids that was recognized in the early days of nutrition as an essential nutrient in food but is inexplicably unacknowledged today. While vitamin F works synergistically with thyroxine to help prevent cancer, Dr. Lee says, one substance that should be avoided is anterior pituitary growth hormone, or “human growth hormone” (HGH). This compound, popular among bodybuilders and athletes today for its performance enhancement, is a “most potent stimulator of cancer,” he warns, and any product that might contain it should be categorically avoided in treatment of the illness. Published by the Lee Foundation for Nutritional Research, 1955.

Dr. Royal Lee on the “X Factor” of Dr. Price

By Dr. Royal Lee with commentary by Mark R. Anderson

Summary: In the 1930s Dr. Weston Price traveled the globe to study the diets of traditional societies that had yet to start eating modern, processed foods or were in the beginning stages of incorporating them into their culture. Among the many profound nutritional discoveries he made (which he published in his seminal book Nutrition and Physical Degeneration) was the existence of a critical fat-soluble nutrient that was responsible for, among other things, moving calcium from the blood into the tissues, including the bones and teeth. Although Dr. Price was able to measure the effects of this “vitamin-like activator” (which he called Activator X), he was never able to precisely identify its chemical structure. According to nutrition educator and historian Mark R. Anderson, Dr. Royal Lee had no doubt that Price’s X factor was a component of vitamin F, a complex that includes the essential fatty acids. Dr. Lee considered Price’s X factor so important, Anderson adds, that he included it in three of his famous therapeutic food formulas—Cataplex F tablets, Cataplex F perles, and Super EFF. In these excerpts Dr. Lee discusses the relationship between the vitamin F complex and Price’s discovery. Selene River Press, 2005. 

High Blood Cholesterol and Its Control

By Dr. Royal Lee

Summary: While cholesterol has been demonized by modern medicine, wise health practitioners know that it is, in fact, an essential component for the proper functioning of the human body. In this 1956 article, Dr. Royal Lee describes cholesterol’s vital role as a “sealing compound” in controlling the diffusion of substances across cell and blood vessel walls. Dr. Lee condemns hydrogenated fats and refined vegetable oils in particular for disturbing the normal cholesterol balance in the body, one probable cause of their effect being the massive loss of nutrients—including the fat-soluble vitamins A, D, E, and K and the essential-fatty-acid complex vitamin F—incurred during refining. From Natural Food and Farming, 1956.

Do You Want to Lose the Hair on Your Chest?

By Dr. Royal Lee and unknown author

Summary: Two articles featuring quotes and commentary by Dr. Royal Lee that contrast the incredible nutritional value of butter with the equally incredible lack of nutritional value of “oleomargarine” (what we call simply margarine today). In particular, the relationship between vitamin E and pubescent development is discussed, with Dr. Lee reminding readers that “sex development demands vitamin E, and butter is our main source in the American diet.” Dr. Lee presents photos of boys and girls demonstrating the failure of sexual differentiation to occur as a result of nutrient starvation. He also discusses the vital roles of the vitamin F and D complexes—both found naturally and in their entirety in butter but not in margarine—in assimilating and distributing calcium in the body. Lee Foundation for Nutritional Research reprint 59, 1948. Multiple original sources. 

A Discussion of the Forms of Blood Calcium

By Dr. Royal Lee and William A. Hanson

Summary: This booklet is an authoritative presentation on the metabolism of calcium in the blood. It outlines the specific influence of various vitamins, such as vitamins F and D, on the movement and activity of calcium. There is more calcium in the body than all the other minerals added together; this is an important overview on the biochemical flow of our most abundant mineral. Includes a large chart of the flow of calcium throughout the body. Published by the Lee Foundation for Nutritional Research, 1942.

View PDF: A Discussion of the Forms of Blood Calcium

Discovery of the Anticancerous Properties of the “F” Vitamine (Reptiline)

By Professor Humberto Aviles

Summary: A sweeping report on the special properties of vitamin F, a complex of essential fatty acids (linolenic acid, linoleic acid, arachidonic adic) that was first identified in 1929 by Drs. Burr and Burr. Though medical and government authorities never recognized the F complex as a vitamin, the author of this paper, along with many other clinicians and particularly Dr. Royal Lee, conducted significant experiments over many decades to prove its presence and effect in the human body. (Today linolenic and linoleic acids are acknowledged by conventional science as the “essential fatty acids.”) Here Professor Aviles, in discussing his own clinical application of vitamin F in relieving pain in cancer patients, presents an extensive review of peer-reviewed literature on vitamin F from around the world, including research in Germany, England, Russia, and the United States. In addition to numerous references, Aviles includes a fascinating time line of the research on fatty acids and cancer from 1924 to 1953. From the Center of Investigations of Medicinal Plants and Animals (Mexico), 1953. Lee Foundation for Nutritional Research special reprint 12-53.

View PDF: Discovery of the Anticancerous Properties of the “F” Vitamine (Reptiline)

Cost of Malnutrition

By Dr. Royal Lee

Summary: In this creative and forward-thinking commentary on preventive healthcare, Dr. Royal Lee discusses the ways in which proper nutrition saves businesses money by fostering employee health. Getting enough vitamin A complex, for instance, helps maintain the integrity of mucous membranes and thus prevents infection and lost man hours. Sufficient vitamin B complex keeps the nerves and heart functioning properly, while adequate vitamin C complex promotes stamina by optimizing the oxygen-carrying capacity of the blood. A proper amount of vitamin D complex prevents cramps, irritability, and bone-calcium loss, and so on. From Let’s Live magazine, 1958.

Protomorphology: The Principles of Cell Auto-Regulation

By Royal Lee and William A. Hanson

Summary: The complete book on the subject of the Protomorphogen. In this seminal work, Dr. Royal Lee connects the dots between the endocrine, nutritional, and cellular control mechanisms of the living human cell as well as how growth and repair in the body are regulated. This is the basis for Dr. Lee’s theories of autoimmune disorders, in which he detailed the immune system’s ability and tendency, under conditions such as nutrient deficiency, to target the body’s own tissue. Lee’s visionary tome was released decades before any understanding of autoimmune disorder was acknowledged or accepted by medicine or any other field of healing. Lee Foundation for Nutritional Research, 1947.

View PDF: Protomorphology: The Principles of Cell Auto-Regulation

Vitamins in Dental Care

By Dr. Royal Lee

Summary: Originally published in Health Culture, this 1955 article outlines the critical roles of natural vitamin complexes, such as vitamins A, B, C, D and F, in maintaining and restoring dental health. Dr. Lee specifically credits the research of the celebrated Dr. Weston Price: “Dr. Weston A. Price was the first dentist to publish an article asserting that dental caries was primarily a result of vitamin deficiency. This was in 1927. In 1923, I had prepared a paper on the subject of ‘The Systemic Cause of Dental Caries,’ and read it to the senior class of Marquette Dental College, subscribing to the same hypothesis.” Amazingly, conventional dentistry still fails to comprehend the basic truth that a properly nourished body is resistant to tooth decay. Reprint 30G, 1955.

This Molasses War—Who Is Prevaricating? and
Bone Meal—Nutritional Source of Calcium

By Dr. Royal Lee

Summary: Two articles that appeared in Let’s Live magazine in 1952 and 1953. In “This Molasses War—Who is Prevaricating?,” Dr. Lee compares natural and refined sugars. He posits that carbohydrates are not essential in the human diet and offers proof by way of certain traditional peoples who eat no carbs and yet experience perfect health. He also discusses the virtues of molasses, which is rich in minerals and is protective against tooth decay, whereas white sugar promotes cavities. Lee also describes the famous experiments of Dr. Rosalind Wulzen of Oregon State College that led to the discovery of the “anti-arthritic factor” in molasses and raw cream that was later named after her. In “Bone Meal—Nutritional Source of Calcium,” Dr. Lee describes the virtues of finely powdered bone flour as a source of protein and minerals, particularly calcium. He states that for the teeth, cold-processed bone meal is unexcelled. He also discusses the role of trace minerals also found in bone meal. 1953.

Vitamins in Dentistry

By Dr. Royal Lee

Summary: A classic Royal Lee document, read before a New York dental group in 1940. In it Dr. Lee outlines how far the understanding of nutrition and dental health had come and how poorly the dental profession had stayed current with this advance of knowledge. He cites many examples—fully referenced—of the direct effect of nutrients on dental health. A great paper if anyone bothered to read and understand it. “Drill ’em and fill ’em” was the dental mantra then, as it is today. Reprint 30B, 1940.