Summary: A riveting article documenting the success of vitamin E therapy in the treatment of heart disease, published by the British journal Popular Science Digest. The key to this success, the authors emphasize, is the use of natural vitamin E over synthetic, the former having been shown to be “highly effective in the treatment of coronary disease, the incidence of which appears to be linked with a deficiency of vitamin E in the diet dating from the beginning of the century, when millers discarded vitamin E in the processing of grain.” While the authors mistakenly confuse isolated natural alpha-tocopherol with the natural vitamin E complex (which includes alpha-tocopherol but other factors in addition), they sum the case for natural vitamin therapy over pharmaceutical drugs brilliantly: “Alpha tocopherol (vitamin E) therapy has the distinctive feature of improving the function of damaged hearts by attacking the underlying pathological changes. Heretofore, the drugs at the disposal of the cardiologist such as digitalis, quinidine, the mercurial diuretics, and nitro-glycerine have helped to re-establish more normal function, but have left the basic pathology unaltered.” In other words, vitamins treat the cause, not the symptoms, as drugs do. The overwhelming clinical success reported in treating heart disease with vitamin E, the article concludes, “is a case for the closest and completely unbiased examination, by those competent to do so, of the claims of those who have developed and sponsored vitamin E therapy.” Words that still ring true today. From Popular Science Digest, 1953. Lee Foundation for Nutritional Research reprint 40A.